With
the advent of Human Genome project, there is an explosion of data on genes and
molecular markers, while combinatorial synthesis is yielding multitude of
potential target compounds. Similarly, there is a perennial need for sensor and
diagnostics systems for improved sensitivity, selectivity and wider deployment,
for biochemical analytes. In this theme, we harness the unique of
bio-nano-structures by integrating them on "engineering" platform, such as
microelectronics.
Our approach is to utilize MOSFET-embedded microcantilevers and MEMS integrated gas sensor system for improved detection of biomolecular binding and gas sensing using label- and optics-free engineered nanosystems.
Here we invoke the electronic signal transduction schemes, coupled with advances in microelectronic integration for building engineered devices and systems, amenable for handheld and wider deployment.
Representative Publications:
- Su M, Dravid VP, "Surface combustion microengines based on photocatalytic oxidations of hydrocarbons at room temperature", Nano Letters 5 (10): 2023-2028 (2005)
- Shekhawat G., Tark S, Dravid VP, "MOSFET-Embedded microcantilever for measuring biomolecular deflection", Science, 311, 1592 (2006)
- Srivastava AK, Dravid VP, "On the performance evaluation of hybrid and mono-class sensor arrays in selective detection of VOCs: A comparative study", Sensors & Actuators B-Chemical 117 (1): 244-252 (2006)
Links to Other Dravid Group Research Themes: