Materials Science and Engineering
Room: B560, Silverman Hall
Chemistry of Life Processes Institute
2170 Campus Drive
Evanston IL, 60208-3113
Phone: (847) 467-2651 (L)
Facsimile: (847) 467-6573
|2009||Ph.D., Materials Science & Engineering
|2003||B.S. Materials Science & Engineering
State University of New York at Stony Brook
|Stony Brook, NY|
Research Objective(s) and Approach
- Fundamental/quantitative validation of the new electronic signal transduction and detection paradigm based on the MOSFET-embedded microcantilevers.
- Simulation and experimental studies to improve and optimize sensor platform performance.
- Evaluation of sensitivity, selectivity, and reproducibility of the MOSFET cantilever sensor platform with biomolecular and chemical detection experiments.
- Cross-validation of MOSFET-embedded cantilever sensing performance with conventional optical deflection detection approach.
- Optimization and application of novel receptors and their immobilization strategies for biological and chemical detection on microcantilevers.
- New electronic, label- and optics-free signal transduction based on MOSFET-embedded cantilevers allows real-time detection of biomolecular interactions with high sensitivity and selectivity by simple direct current measurement as demonstrated in the following results.
- Shekhawat G, Tark S, Dravid VP, "MOSFET-Embedded Microcantilevers for Measuring Deflection in Biomolecular Sensors", Science, 311 (5767): pp: 1592-1595 (2006)
- Tark S, Srivastava A, Chou S, Shekhawat G, Dravid VP, "Nanomechanoelectronic Signal Transduction Scheme with Metal-Oxide-Semiconductor Field-Effect Transistor-Embedded Microcantilevers", Applied Physics Letters, Vol. 94 (10): article: 104101: DOI:10.1063/1.3093874 (2009)